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NGS system

The Ion Proton™ System minimizes the high cost and complexity of high-throughput sequencing, bringing it to your research lab, on your budget, and on your schedule. This system enables high-quality exome and transcriptome sequencing in just a few day

Contacts and Location

Contact 1 Dāvid Fridmanis
Contact 2 Vita Rovīte
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Organisational Unit Latvian Biomedical Research and Study Centre - Latvia

Description

The Ion Proton™ System is the first benchtop sequencing system capable of human-scale genome, exome, or transcriptome sequencing in a few hours—with DNA-to-variants called in a single day. The system combines semiconductor sequencing technology with natural biochemistry to directly translate chemical information into digital data. By leveraging the exponential improvements in the semiconductor industry (known as Moore’s Law), the Ion Proton™ Sequencing System provides an unprecedented level of scalability and flexibility to support a broad range of high throughput sequencing applications, ranging from human-scale genome to exome to transcriptome sequencing. The system’s use of the simplest natural sequencing chemistry eliminates the need for expensive optics and complex sequencing chemistries, resulting in a highly affordable sequencing system to own and operate. Real-time, direct, electrical detection of sequencing, combined with the enormous amount of computing power in both the Ion Proton™ Sequencer and Ion Proton™ Torrent Server, enables generation of high quality sequencing results from DNA library to variants in a single day.

Specification

"Technique: Post-Light™ Ion Semiconductor Sequencing Output: Ion Proton I Chip: Up to 2 human exomes per run Throughput: Up to 10 Gb per run (Ion Proton I Chip) Read Length: Up to 200 bp Capacity: 1 chip per run Chip Compatibility: Ion PI™ Chip Run Time: 2-4 hours Reads⁄Run: Ion Proton I Chip: 60-80 million reads (passing filter at ≥50 bases) Multiplex Capability: RNA: 16 off-the-shelf barcodes, Up to 384 barcodes, DNA: 96 off-the-shelf barcodes Data Output: VCF Files, FASTQ Files, BAM Files, SFF Files "

Services

Exome and transcriptome sequencing

Status

Available as service
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