Laser Capture Microdissection System

Laser Capture Microdissection(LCM)is an instrument to isolate specific single cells or entire areas of tissue. Powered by a unique laser design and dynamic software, LCM system allows users to easily isolate regions of interest from entire areas of tissue down to single cells or even subcellular structures such as chromosomes.

Specification:

• Scanning area: 120x100 mm2
• Repositioning accuracy: < 1 μm
• Step resolution: 0.078 μm
• Laser System
• Wavelength: 355 nm
• Line voltage: 200–240 VAC or 100–110 VAC, 50–60 Hz, 1,0 A
• mmi Cell Camera MXF285c
• CCD camera: IEEE1394a (FireWire) interline transfer color
• CCD readout: 2/3" interline transfer frame
• Signal to noise ratio: > 56 dB
• mmi CapLift
• moving distance: 3 mm
• cap pressure: adjustable
• accuracy: high repositioning

LCM is a one-step process that provides a fast method of preserving and isolating single cells or clusters of cells from tissue sections by direct microscopic visualisation without contaminating cells to perform accurate assays on specific single cell using the following applications:

• DNA genotyping and loss-of-heterozygosity (LOH) analysis
• RNA transcript profiling
• cDNA library generation
• Proteomics discovery and signal-pathway profiling.